2011年7月26日 星期二

Physiology and immunology of the cholinergic antiinflammatory pathway

   
 (點擊上方圖片進入王群光自然診所官網)

王群光自然診所:台北市羅斯福路三段271號10樓
諮詢電話:886-2-23671086
LINE ID:0919730053
 Wechat ID: a0919730053


Kevin J. Tracey


Abstract

Cytokine production by the immune system contributes importantly to both health and disease. The nervous system, via an inflammatory reflex of the vagus nerve, can inhibit cytokine release and thereby prevent tissue injury and death. The efferent neural signaling pathway is termed the cholinergic antiinflammatory pathway. Cholinergic agonists inhibit cytokine synthesis and protect against cytokine-mediated diseases. Stimulation of the vagus nerve prevents the damaging effects of cytokine release in experimental sepsis, endotoxemia, ischemia/reperfusion injury,
hemorrhagic shock, arthritis, and other inflammatory syndromes. Herein is a review of this physiological, functional anatomical mechanism for neurological regulation of cytokine-dependent disease that begins to define an immunological homunculus.

檔案下載

   
 (點擊上方圖片進入王群光自然診所官網)

沒有留言:

張貼留言